How change mutationObserver on created controller?

How change mutationObserver on created controller? If i create div element with data-controller attribute and want dynamically change tracking from
this.mutationObserver.observe(this.element, { attributes: true, childList: true, subtree: true })
on a
this.mutationObserver.observe(this.element, { attributes: true, childList: true, subtree: false })